The muscle-specific microRNA miR-206 blocks human rhabdomyosarcoma growth in xenotransplanted mice by promoting myogenic differentiation

Many microRNAs (miRNAs), posttranscriptional regulators of numerous cellular processes and developmental events, are downregulated in tumors. However, their role in tumorigenesis remains largely unknown. In this work, we examined the role of the muscle-specific miRNAs miR-1 and miR-206 in human rhab...

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Detalhes bibliográficos
Main Authors: Taulli, Riccardo, Bersani, Francesca, Foglizzo, Valentina, Linari, Alessandra, Vigna, Elisa, Ladanyi, Marc, Tuschl, Thomas, Ponzetto, Carola
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719932/
https://ncbi.nlm.nih.gov/pubmed/19620785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38075
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