The muscle-specific microRNA miR-206 blocks human rhabdomyosarcoma growth in xenotransplanted mice by promoting myogenic differentiation

Many microRNAs (miRNAs), posttranscriptional regulators of numerous cellular processes and developmental events, are downregulated in tumors. However, their role in tumorigenesis remains largely unknown. In this work, we examined the role of the muscle-specific miRNAs miR-1 and miR-206 in human rhab...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Taulli, Riccardo, Bersani, Francesca, Foglizzo, Valentina, Linari, Alessandra, Vigna, Elisa, Ladanyi, Marc, Tuschl, Thomas, Ponzetto, Carola
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2009
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719932/
https://ncbi.nlm.nih.gov/pubmed/19620785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38075
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