Connexin 32 dysfunction promotes ethanol-related hepatocarcinogenesis via activation of Dusp1-Erk axis

There is abundant epidemiological evidence that heavy alcohol intake contributes to hepatocellular carcinoma (HCC) development. Previous reports indicated that connexin 32 (Cx32), which is a major hepatocyte gap junction protein, is down-regulated in chronic liver disease and has a protective role i...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Kato, Hiroyuki, Naiki-Ito, Aya, Naiki, Taku, Suzuki, Shugo, Yamashita, Yoriko, Sato, Shinya, Sagawa, Hiroyuki, Kato, Akihisa, Kuno, Toshiya, Takahashi, Satoru
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811513/
https://ncbi.nlm.nih.gov/pubmed/26655499
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