Targeting oncogenic PLCE1 by miR-145 impairs tumor proliferation and metastasis of esophageal squamous cell carcinoma

Phospholipase C epsilon 1 (PLCE1) is a susceptibility gene in esophageal squamous cell carcinoma (ESCC). Nevertheless, the role of PLCE1 in ESCC tumorigenesis has not been elucidated. In this study, we determined the function of PLCE1 and its regulatory microRNA (miRNA) in ESCC. PLCE1 protein was ex...

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Udgivet i:Oncotarget
Main Authors: Cui, Xiao-Bin, Li, Su, Li, Ting-Ting, Peng, Hao, Jin, Ting-Ting, Zhang, Shu-Mao, Liu, Chun-Xia, Yang, Lan, Shen, Yao-Yuan, Li, Shu-Gang, Li, Na, Li, Yong, Hu, Jian-Ming, Jiang, Jin-Fang, Suo, Jing, Qi, Yan, Liang, Wei-Hua, Wang, Liang-Hai, Dang, Hong-Wei, Li, Li, Cao, Wei-Wei, Wei, Yutao, Yin, Laibo, Wu, Chuan-Yue, Yuan, Xiang-Lin, Zhou, Hong, Zheng, Yu, Chen, Yun-Zhao, Li, Feng
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811497/
https://ncbi.nlm.nih.gov/pubmed/26657507
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