Targeting oncogenic PLCE1 by miR-145 impairs tumor proliferation and metastasis of esophageal squamous cell carcinoma

Phospholipase C epsilon 1 (PLCE1) is a susceptibility gene in esophageal squamous cell carcinoma (ESCC). Nevertheless, the role of PLCE1 in ESCC tumorigenesis has not been elucidated. In this study, we determined the function of PLCE1 and its regulatory microRNA (miRNA) in ESCC. PLCE1 protein was ex...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Cui, Xiao-Bin, Li, Su, Li, Ting-Ting, Peng, Hao, Jin, Ting-Ting, Zhang, Shu-Mao, Liu, Chun-Xia, Yang, Lan, Shen, Yao-Yuan, Li, Shu-Gang, Li, Na, Li, Yong, Hu, Jian-Ming, Jiang, Jin-Fang, Suo, Jing, Qi, Yan, Liang, Wei-Hua, Wang, Liang-Hai, Dang, Hong-Wei, Li, Li, Cao, Wei-Wei, Wei, Yutao, Yin, Laibo, Wu, Chuan-Yue, Yuan, Xiang-Lin, Zhou, Hong, Zheng, Yu, Chen, Yun-Zhao, Li, Feng
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2015
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811497/
https://ncbi.nlm.nih.gov/pubmed/26657507
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