PFN2, a novel marker of unfavorable prognosis, is a potential therapeutic target involved in esophageal squamous cell carcinoma

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is one of the most aggressively malignant tumors with dismal prognosis. Profilin 2 (PFN2) is an actin-binding protein that regulates the dynamics of actin polymerization and plays a key role in cell motility. Recently, PFN2 have emerged as signif...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Cui, Xiao-bin, Zhang, Shu-mao, Xu, Yue-xun, Dang, Hong-wei, Liu, Chun-xia, Wang, Liang-hai, Yang, Lan, Hu, Jian-ming, Liang, Wei-hua, Jiang, Jin-fang, Li, Na, Li, Yong, Chen, Yun-zhao, Li, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870769/
https://ncbi.nlm.nih.gov/pubmed/27188458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0884-y
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