The protein kinase LKB1 negatively regulates bone morphogenetic protein receptor signaling

The protein kinase LKB1 regulates cell metabolism and growth and is implicated in intestinal and lung cancer. Bone morphogenetic protein (BMP) signaling regulates cell differentiation during development and tissue homeostasis. We demonstrate that LKB1 physically interacts with BMP type I receptors a...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Raja, Erna, Tzavlaki, Kalliopi, Vuilleumier, Robin, Edlund, Karolina, Kahata, Kaoru, Zieba, Agata, Morén, Anita, Watanabe, Yukihide, Voytyuk, Iryna, Botling, Johan, Söderberg, Ola, Micke, Patrick, Pyrowolakis, George, Heldin, Carl-Henrik, Moustakas, Aristidis
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper: Pathology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811448/
https://ncbi.nlm.nih.gov/pubmed/26701726
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