The protein kinase LKB1 negatively regulates bone morphogenetic protein receptor signaling

The protein kinase LKB1 regulates cell metabolism and growth and is implicated in intestinal and lung cancer. Bone morphogenetic protein (BMP) signaling regulates cell differentiation during development and tissue homeostasis. We demonstrate that LKB1 physically interacts with BMP type I receptors a...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Raja, Erna, Tzavlaki, Kalliopi, Vuilleumier, Robin, Edlund, Karolina, Kahata, Kaoru, Zieba, Agata, Morén, Anita, Watanabe, Yukihide, Voytyuk, Iryna, Botling, Johan, Söderberg, Ola, Micke, Patrick, Pyrowolakis, George, Heldin, Carl-Henrik, Moustakas, Aristidis
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2015
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Research Paper: Pathology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811448/
https://ncbi.nlm.nih.gov/pubmed/26701726
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