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The high mobility group A2 protein epigenetically silences the Cdh1 gene during epithelial-to-mesenchymal transition
The loss of the tumour suppressor E-cadherin (Cdh1) is a key event during tumourigenesis and epithelial–mesenchymal transition (EMT). Transforming growth factor-β (TGFβ) triggers EMT by inducing the expression of non-histone chromatin protein High Mobility Group A2 (HMGA2). We have previously shown...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4288184/ https://ncbi.nlm.nih.gov/pubmed/25492890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1293 |
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