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PTF1a Activity in Enriched Posterior Foregut Endoderm, but Not Definitive Endoderm, Leads to Enhanced Pancreatic Differentiation in an In Vitro Mouse ESC-Based Model

Transcription factors are tools repetitively used by the embryo to generate a variety of lineages. Hence, their context of activation is an important determinant of their ability to specifically trigger certain cell fates, but not others. The context is also consequential when considering directing...

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Detalhes bibliográficos
Publicado no:Stem Cells Int
Main Authors: Nair, Gopika G., Odorico, Jon S.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811216/
https://ncbi.nlm.nih.gov/pubmed/27066080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/6939438
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