Elimination of Tumorigenic Stem Cells from Differentiated Progeny and Selection of Definitive Endoderm Reveals a Pdx1(+) Foregut Endoderm Stem Cell Lineage

Embryonic stem cell (ESC) derivatives offer promise for generating clinically useful tissues for transplantation, yet the specter of producing tumors in patients remains a significant concern. We have developed a simple method that eliminates the tumorigenic potential from differentiated ESC culture...

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Détails bibliographiques
Auteurs principaux: Kahan, Brenda, Magliocca, Joseph, Merriam, Fabiola, Treff, Nathan, Budde, Melisa, Nelson, Jeffrey, Browning, Victoria, Ziehr, Benjamin, Odorico, Jon
Format: Artigo
Langue:Inglês
Publié: 2010
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040268/
https://ncbi.nlm.nih.gov/pubmed/21130058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2010.10.003
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