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The Translational Repressor 4E-BP1 Contributes to Diabetes-Induced Visual Dysfunction
PURPOSE: The translational repressor 4E-BP1 interacts with the mRNA cap-binding protein eIF4E and thereby promotes cap-independent translation of mRNAs encoding proteins that contribute to diabetic retinopathy. Interaction of 4E-BP1 with eIF4E is enhanced in the retina of diabetic rodents, at least...
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| Publicado no: | Invest Ophthalmol Vis Sci |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Association for Research in Vision and Ophthalmology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4811182/ https://ncbi.nlm.nih.gov/pubmed/26998719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-18719 |
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