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Intranasal Introduction of Fc-Fused Interleukin-7 Provides Long-Lasting Prophylaxis against Lethal Influenza Virus Infection

Influenza A virus (IAV) infection frequently causes hospitalization and mortality due to severe immunopathology. Annual vaccination and antiviral drugs are the current countermeasures against IAV infection, but they have a limited efficacy against new IAV variants. Here, we show that intranasal pret...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Kang, Moon Cheol, Choi, Dong-Hoon, Choi, Young Woo, Park, Seong Jeong, Namkoong, Hong, Park, Ki Seok, Ahn, So-Shin, Surh, Charles D., Yoon, Sun-Woo, Kim, Doo-Jin, Choi, Jung-ah, Park, Yunji, Sung, Young Chul, Lee, Seung-Woo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810684/
https://ncbi.nlm.nih.gov/pubmed/26656713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02768-15
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