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In vivo RNAi screens: concepts and applications
Functional genomics approaches that leverage the RNA interference (RNAi) pathway have been applied in vivo to examine the roles of hundreds or thousands of genes, mainly in the context of cancer. Here we discuss principles guiding the design of RNAi screens, parameters that determine success and rec...
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| Udgivet i: | Trends Immunol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4810674/ https://ncbi.nlm.nih.gov/pubmed/25937561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2015.03.007 |
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