Human Cytomegalovirus Stimulates the Synthesis of Select Akt-Dependent Antiapoptotic Proteins during Viral Entry To Promote Survival of Infected Monocytes

Primary peripheral blood monocytes are responsible for the hematogenous dissemination of human cytomegalovirus (HCMV) following a primary infection. To facilitate viral spread, we have previously shown HCMV to extend the short 48-h life span of monocytes. Mechanistically, HCMV upregulated two specif...

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Vydáno v:J Virol
Hlavní autoři: Peppenelli, Megan A., Arend, Kyle C., Cojohari, Olesea, Moorman, Nathaniel J., Chan, Gary C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810618/
https://ncbi.nlm.nih.gov/pubmed/26739047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02879-15
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