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Inhibition of the FACT Complex Reduces Transcription from the Human Cytomegalovirus Major Immediate Early Promoter in Models of Lytic and Latent Replication

The successful colonization of the majority of the population by human cytomegalovirus is a direct result of the virus's ability to establish and, more specifically, reactivate from latency. The underlying cellular factors involved in viral reactivation remain unknown. Here, we show that the ho...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: O'Connor, Christine M., Nukui, Masatoshi, Gurova, Katerina V., Murphy, Eain A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810550/
https://ncbi.nlm.nih.gov/pubmed/26865717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02501-15
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