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Host MicroRNA Regulation of Human Cytomegalovirus Immediate Early Protein Translation Promotes Viral Latency

Reactivation of human cytomegalovirus (HCMV) is a significant cause of disease and death in immunocompromised patients, underscoring the need to understand how latency is controlled. Here we demonstrate that HCMV has evolved to utilize cellular microRNAs (miRNAs) in cells that promote latency to reg...

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Detalhes bibliográficos
Main Authors: O'Connor, Christine M., Vanicek, Jiri, Murphy, Eain A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019081/
https://ncbi.nlm.nih.gov/pubmed/24599990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00481-14
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