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A Switch in Akt Isoforms Is Required for Notch-Induced Snail1 Expression and Protection from Cell Death
Notch activation in aortic endothelial cells (ECs) takes place at embryonic stages during cardiac valve formation and induces endothelial-to-mesenchymal transition (EndMT). Using aortic ECs, we show here that active Notch expression promotes EndMT, resulting in downregulation of vascular endothelial...
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| Publicado en: | Mol Cell Biol |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4810475/ https://ncbi.nlm.nih.gov/pubmed/26711268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01074-15 |
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