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Glycosyltransferases and Transpeptidases/Penicillin-Binding Proteins: Valuable Targets for New Antibacterials

Peptidoglycan (PG) is an essential macromolecular sacculus surrounding most bacteria. It is assembled by the glycosyltransferase (GT) and transpeptidase (TP) activities of multimodular penicillin-binding proteins (PBPs) within multiprotein complex machineries. Both activities are essential for the s...

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Detalhes bibliográficos
Publicado no:Antibiotics (Basel)
Main Authors: Sauvage, Eric, Terrak, Mohammed
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810414/
https://ncbi.nlm.nih.gov/pubmed/27025527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antibiotics5010012
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