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Peptidoglycan Glycosyltransferase Substrate Mimics as Templates for the Design of New Antibacterial Drugs

Peptidoglycan (PG) is an essential net-like macromolecule that surrounds bacteria, gives them their shape, and protects them against their own high osmotic pressure. PG synthesis inhibition leads to bacterial cell lysis, making it an important target for many antibiotics. The final two reactions in...

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Detalhes bibliográficos
Main Authors: Derouaux, Adeline, Sauvage, Eric, Terrak, Mohammed
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3608906/
https://ncbi.nlm.nih.gov/pubmed/23543824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00078
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