Analgesic Effects of GpTx-1, PF-04856264 and CNV1014802 in a Mouse Model of Na(V)1.7-Mediated Pain

Loss-of-function mutations of Na(V)1.7 lead to congenital insensitivity to pain, a rare condition resulting in individuals who are otherwise normal except for the inability to sense pain, making pharmacological inhibition of Na(V)1.7 a promising therapeutic strategy for the treatment of pain. We cha...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Main Authors: Deuis, Jennifer R., Wingerd, Joshua S., Winter, Zoltan, Durek, Thomas, Dekan, Zoltan, Sousa, Silmara R., Zimmermann, Katharina, Hoffmann, Tali, Weidner, Christian, Nassar, Mohammed A., Alewood, Paul F., Lewis, Richard J., Vetter, Irina
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810223/
https://ncbi.nlm.nih.gov/pubmed/26999206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins8030078
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