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Application and Optimization of relE as a Negative Selection Marker for Making Definitive Genetic Constructs in Uropathogenic Escherichia coli

Studies of Uropathogenic Escherichia coli (UPEC) pathogenesis have relied heavily on genetic manipulation to understand virulence factors. We applied a recently reported positive-negative selection system to create a series of unmarked, scarless FimH mutants that show identical phenotypes to previou...

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Detalhes bibliográficos
Publicado no:Pathogens
Main Authors: Khetrapal, Varnica, Mehershahi, Kurosh S., Chen, Siyi, Chen, Swaine L.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810130/
https://ncbi.nlm.nih.gov/pubmed/26797639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pathogens5010009
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