Development of Exosome-encapsulated Paclitaxel to Overcome MDR in Cancer cells

Exosomes have recently come into focus as “natural nanoparticles” for use as drug delivery vehicles. Our objective was to assess the feasibility of an exosome-based drug delivery platform for a potent chemotherapeutic agent, paclitaxel (PTX), to treat MDR cancer. Herein, we developed and compared di...

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Pubblicato in:Nanomedicine
Autori principali: Kim, Myung Soo, Haney, Matthew J., Zhao, Yuling, Mahajan, Vivek, Deygen, Irina, Klyachko, Natalia L., Inskoe, Eli, Piroyan, Aleksandr, Sokolsky, Marina, Okolie, Onyi, Hingtgen, Shawn D., Kabanov, Alexander V., Batrakova, Elena V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4809755/
https://ncbi.nlm.nih.gov/pubmed/26586551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2015.10.012
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