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Development of Exosome-encapsulated Paclitaxel to Overcome MDR in Cancer cells

Exosomes have recently come into focus as “natural nanoparticles” for use as drug delivery vehicles. Our objective was to assess the feasibility of an exosome-based drug delivery platform for a potent chemotherapeutic agent, paclitaxel (PTX), to treat MDR cancer. Herein, we developed and compared di...

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Publicado en:Nanomedicine
Autores principales: Kim, Myung Soo, Haney, Matthew J., Zhao, Yuling, Mahajan, Vivek, Deygen, Irina, Klyachko, Natalia L., Inskoe, Eli, Piroyan, Aleksandr, Sokolsky, Marina, Okolie, Onyi, Hingtgen, Shawn D., Kabanov, Alexander V., Batrakova, Elena V.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4809755/
https://ncbi.nlm.nih.gov/pubmed/26586551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2015.10.012
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