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Quantitative Gait Analysis Using a Motorized Treadmill System Sensitively Detects Motor Abnormalities in Mice Expressing ATPase Defective Spastin

The hereditary spastic paraplegias (HSPs) are genetic conditions in which there is progressive axonal degeneration in the corticospinal tract. Autosomal dominant mutations, including nonsense, frameshift and missense changes, in the gene encoding the microtubule severing ATPase spastin are the most...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Connell, James W., Allison, Rachel, Reid, Evan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4809716/
https://ncbi.nlm.nih.gov/pubmed/27019090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152413
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