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Quantitative Gait Analysis Using a Motorized Treadmill System Sensitively Detects Motor Abnormalities in Mice Expressing ATPase Defective Spastin

The hereditary spastic paraplegias (HSPs) are genetic conditions in which there is progressive axonal degeneration in the corticospinal tract. Autosomal dominant mutations, including nonsense, frameshift and missense changes, in the gene encoding the microtubule severing ATPase spastin are the most...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Connell, James W., Allison, Rachel, Reid, Evan
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4809716/
https://ncbi.nlm.nih.gov/pubmed/27019090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152413
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