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ESCRT-III-associated proteins and spastin inhibit protrudin-dependent polarised membrane traffic

Mutations in the gene encoding the microtubule severing ATPase spastin are the most frequent cause of hereditary spastic paraplegia, a genetic condition characterised by length-dependent axonal degeneration. Here, we show that HeLa cells lacking spastin and embryonic fibroblasts from a spastin knock...

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Detalhes bibliográficos
Publicado no:Cell Mol Life Sci
Main Authors: Connell, James W., Allison, Rachel J., Rodger, Catherine E., Pearson, Guy, Zlamalova, Eliska, Reid, Evan
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7320071/
https://ncbi.nlm.nih.gov/pubmed/31587092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-019-03313-z
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