Systematic Comparative Evaluation of Methods for Investigating the TCRβ Repertoire

High-throughput sequencing has recently been applied to profile the high diversity of antibodyome/B cell receptors (BCRs) and T cell receptors (TCRs) among immune cells. To date, Multiplex PCR (MPCR) and 5’RACE are predominately used to enrich rearranged BCRs and TCRs. Both approaches have advantage...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Liu, Xiao, Zhang, Wei, Zeng, Xiaojing, Zhang, Ruifang, Du, Yuanping, Hong, Xueyu, Cao, Hongzhi, Su, Zheng, Wang, Changxi, Wu, Jinghua, Nie, Chao, Xu, Xun, Kristiansen, Karsten
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4809601/
https://ncbi.nlm.nih.gov/pubmed/27019362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152464
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