Phosphorylation by Protein Kinase CK2 Changes the DNA Binding Properties of the Human Chromatin Protein DEK

We have examined the posttranslational modification of the human chromatin protein DEK and found that DEK is phosphorylated by the protein kinase CK2 in vitro and in vivo. Phosphorylation sites were mapped by quadrupole ion trap mass spectrometry and found to be clustered in the C-terminal region of...

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Autors principals: Kappes, Ferdinand, Damoc, Catalina, Knippers, Rolf, Przybylski, Michael, Pinna, Lorenzo A., Gruss, Claudia
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Gene Expression
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC480878/
https://ncbi.nlm.nih.gov/pubmed/15199154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.13.6011-6020.2004
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