Phosphorylation by Protein Kinase CK2 Changes the DNA Binding Properties of the Human Chromatin Protein DEK

We have examined the posttranslational modification of the human chromatin protein DEK and found that DEK is phosphorylated by the protein kinase CK2 in vitro and in vivo. Phosphorylation sites were mapped by quadrupole ion trap mass spectrometry and found to be clustered in the C-terminal region of...

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Detalhes bibliográficos
Main Authors: Kappes, Ferdinand, Damoc, Catalina, Knippers, Rolf, Przybylski, Michael, Pinna, Lorenzo A., Gruss, Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC480878/
https://ncbi.nlm.nih.gov/pubmed/15199154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.13.6011-6020.2004
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