Phosphorylation by Protein Kinase CK2 Changes the DNA Binding Properties of the Human Chromatin Protein DEK

We have examined the posttranslational modification of the human chromatin protein DEK and found that DEK is phosphorylated by the protein kinase CK2 in vitro and in vivo. Phosphorylation sites were mapped by quadrupole ion trap mass spectrometry and found to be clustered in the C-terminal region of...

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Bibliographic Details
Main Authors: Kappes, Ferdinand, Damoc, Catalina, Knippers, Rolf, Przybylski, Michael, Pinna, Lorenzo A., Gruss, Claudia
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC480878/
https://ncbi.nlm.nih.gov/pubmed/15199154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.13.6011-6020.2004
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