OCD is associated with an altered association between sensorimotor gating and cortical and subcortical 5-HT1b receptor binding

Obsessive-compulsive disorder (OCD) is characterized by impaired sensorimotor gating, as measured using prepulse inhibition (PPI). This effect may be related to abnormalities in the serotonin (5-HT) system. 5-HT(1B) agonists can impair PPI, produce OCD-like behaviors in animals, and exacerbate OCD s...

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Detalhes bibliográficos
Publicado no:J Affect Disord
Main Authors: Pittenger, Christopher, Adams, Thomas. G., Gallezot, Jean-Dominique, Crowley, Michael J., Nabulsi, Nabeel, Ropchan, James, Gao, Hong, Kichuk, Stephen A., Simpson, Ryan, Billingslea, Eileen, Hannestad, Jonas, Bloch, Michael, Mayes, Linda, Bhagwagar, Zubin, Carson, Richard E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808438/
https://ncbi.nlm.nih.gov/pubmed/26919057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jad.2016.02.021
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