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ASSESSING THE SENSITIVITY OF [(11)C]P943, A NOVEL 5-HT(IB) PET RADIOLIGAND, TO ENDOGENOUS SEROTONIN RELEASE
The main objective of the current study was to determine the sensitivity of the PET radioligand [(11)C]P943 to fenfluramine-induced changes in endogenous 5-HT in nonhuman primate brain. Fenfluramine-induced changes in 5-HT(1B) occupancy were compared to those obtained by self-block with unlabeled P9...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3149753/ https://ncbi.nlm.nih.gov/pubmed/21484884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.20942 |
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