ASSESSING THE SENSITIVITY OF [(11)C]P943, A NOVEL 5-HT(IB) PET RADIOLIGAND, TO ENDOGENOUS SEROTONIN RELEASE

The main objective of the current study was to determine the sensitivity of the PET radioligand [(11)C]P943 to fenfluramine-induced changes in endogenous 5-HT in nonhuman primate brain. Fenfluramine-induced changes in 5-HT(1B) occupancy were compared to those obtained by self-block with unlabeled P9...

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Hlavní autoři: Cosgrove, Kelly P., Kloczynski, Tracy, Nabulsi, Nabeel, Weinzimmer, David, Lin, Shu-fei, Staley, Julie K., Bhagwagar, Zubin, Carson, Richard E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149753/
https://ncbi.nlm.nih.gov/pubmed/21484884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.20942
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