Age-Related Change in 5-HT(6) Receptor Availability in Healthy Male Volunteers Measured with (11)C-GSK215083 PET

Serotonin receptor 6 (5-hydroxytrypamine-6, or 5-HT(6)) is a potential therapeutic target given its distribution in brain regions that are important in depression, anxiety, and cognition. This study sought to investigate the effects of age on 5-HT(6) receptor availability using (11)C-GSK215083, a PE...

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Bibliographic Details
Published in:J Nucl Med
Main Authors: Radhakrishnan, Rajiv, Nabulsi, Nabeel, Gaiser, Edward, Gallezot, Jean-Dominique, Henry, Shannan, Planeta, Beata, Lin, Shu-fei, Ropchan, Jim, Williams, Wendol, Morris, Evan, D’Souza, Deepak Cyril, Huang, Yiyun, Carson, Richard E., Matuskey, David
Format: Artigo
Language:Inglês
Published: Society of Nuclear Medicine 2018
Subjects:
Neurology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6126437/
https://ncbi.nlm.nih.gov/pubmed/29626125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.117.206516
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