2181 Age-related change in 5-HT6 receptor availability in healthy male volunteers measured with 11C-GSK215083 PET

OBJECTIVES/SPECIFIC AIMS: The serotonin receptor 6 (5-HT6) is a potential therapeutic target given its distribution in brain regions that are important in depression, anxiety, and cognition. This study sought to investigate the effects of age on 5-HT6 receptor availability using 11C GSK215083, a PET...

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Detalhes bibliográficos
Publicado no:J Clin Transl Sci
Main Authors: Radhakrishnan, Rajiv, Nabulsi, Nabeel, Gaiser, Edward, Gallezot, Jean-Dominique, Henry, Shannan, Planeta, Beata, Lin, Shu-fei, Ropchan, Jim, Williams, Wendol, Morris, Evan, D’Souza, Deepak Cyril, Huang, Yiyun, Carson, Richard E., Matuskey, David
Formato: Artigo
Idioma:Inglês
Publicado em: Cambridge University Press 2018
Assuntos:
Basic/Translational Science/Team Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6799074/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2018.44
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