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Light-up and FRET aptamer reporters; evaluating their applications for imaging transcription in eukaryotic cells

The regulation of RNA transcription is central to cellular function. Changes in gene expression drive differentiation and cellular responses to events such as injury. RNA trafficking can also have a large impact on protein expression and its localization. Thus, the ability to image RNA transcription...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Methods
Hauptverfasser: Ilgu, Muslum, Ray, Judhajeet, Bendickson, Lee, Wang, Tianjiao, Geraskin, Ivan, Kraus, George A, Nilsen-Hamilton, Marit
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808412/
https://ncbi.nlm.nih.gov/pubmed/26707205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2015.12.009
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