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Aptamer-enabled uptake of small molecule ligands
The relative ease of isolating aptamers with high specificity for target molecules suggests that molecular recognition may be common in the folds of natural RNAs. We show here that, when expressed in cells, aptamers can increase the intracellular concentrations of their small molecule ligands. We ha...
Enregistré dans:
| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6200808/ https://ncbi.nlm.nih.gov/pubmed/30356136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33887-w |
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