The Nonartemisinin Sesquiterpene Lactones Parthenin and Parthenolide Block Plasmodium falciparum Sexual Stage Transmission

Parthenin and parthenolide are natural products that are closely related in structure to artemisinin, which is also a sesquiterpene lactone (SQL) and one of the most important antimalarial drugs available. Parthenin, like artemisinin, has an effect on Plasmodium blood stage development. We extended...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Balaich, Jared N., Mathias, Derrick K., Torto, Baldwyn, Jackson, Bryan T., Tao, Dingyin, Ebrahimi, Babak, Tarimo, Brian B., Cheseto, Xavier, Foster, Woodbridge A., Dinglasan, Rhoel R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2016
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808191/
https://ncbi.nlm.nih.gov/pubmed/26787692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02002-15
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