Hsp72 Is an Intracellular Target of the α,β-Unsaturated Sesquiterpene Lactone, Parthenolide

[Image: see text] The electrophilic natural product parthenolide has generated significant interest as a model for potential chemotherapeutics. Similar to other α,β-unsaturated carbonyl electrophiles, parthenolide induces the heat shock response in leukemia cells, potentially through covalent adduct...

Full description

Saved in:
Bibliographic Details
Published in:ACS Omega
Main Authors: Shin, Myungsun, McGowan, Andrew, DiNatale, Gabriel J., Chiramanewong, Thanprakorn, Cai, Tianyi, Connor, Rebecca E.
Format: Artigo
Language:Inglês
Published: American Chemical Society 2017
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044938/
https://ncbi.nlm.nih.gov/pubmed/30023543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b00954
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items