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Hsp72 Is an Intracellular Target of the α,β-Unsaturated Sesquiterpene Lactone, Parthenolide

[Image: see text] The electrophilic natural product parthenolide has generated significant interest as a model for potential chemotherapeutics. Similar to other α,β-unsaturated carbonyl electrophiles, parthenolide induces the heat shock response in leukemia cells, potentially through covalent adduct...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Shin, Myungsun, McGowan, Andrew, DiNatale, Gabriel J., Chiramanewong, Thanprakorn, Cai, Tianyi, Connor, Rebecca E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044938/
https://ncbi.nlm.nih.gov/pubmed/30023543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b00954
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