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Novel histone deacetylase inhibitor MPT0G009 induces cell apoptosis and synergistic anticancer activity with tumor necrosis factor-related apoptosis-inducing ligand against human hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a frequent cause of cancer-related death; therefore, more effective anticancer therapies for the treatment of HCC are needed. Histone deacetylase (HDAC) inhibitors serve as promising anticancer drugs because they can induce cell growth arrest and apoptosis. We previ...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Chen, Mei-Chuan, Huang, Hui-Hsuan, Lai, Chin-Yu, Lin, Yi-Jyun, Liou, Jing-Ping, Lai, Mei-Jung, Li, Yu-Hsuan, Teng, Che-Ming, Yang, Chia-Ron
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808007/
https://ncbi.nlm.nih.gov/pubmed/26587975
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