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A Disintegrin and Metalloproteinase Domain 17 Regulates Colorectal Cancer Stem Cells and Chemosensitivity Via Notch1 Signaling

Evidence is accumulating for the role of cancer stem cells (CSCs) in mediating chemoresistance in patients with metastatic colorectal cancer (mCRC). A disintegrin and metalloproteinase domain 17 (ADAM17; also known as tumor necrosis factor-α-converting enzyme [TACE]) was shown to be overexpressed an...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Stem Cells Transl Med
मुख्य लेखकों: Wang, Rui, Ye, Xiangcang, Bhattacharya, Rajat, Boulbes, Delphine R., Fan, Fan, Xia, Ling, Ellis, Lee M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: AlphaMed Press 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807666/
https://ncbi.nlm.nih.gov/pubmed/26744411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2015-0168
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