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Discovery of the Elusive UDP-Diacylglucosamine Hydrolase in the Lipid A Biosynthetic Pathway in Chlamydia trachomatis

Constitutive biosynthesis of lipid A via the Raetz pathway is essential for the viability and fitness of Gram-negative bacteria, including Chlamydia trachomatis. Although nearly all of the enzymes in the lipid A biosynthetic pathway are highly conserved across Gram-negative bacteria, the cleavage of...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Young, Hayley E., Zhao, Jinshi, Barker, Jeffrey R., Guan, Ziqiang, Valdivia, Raphael H., Zhou, Pei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807358/
https://ncbi.nlm.nih.gov/pubmed/27006461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00090-16
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