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Non-equivalent Roles of AGO1 and AGO2 in mRNA Turnover and Translation of Cyclin D1 mRNA

Mammalian Argonaute proteins (AGO1–4), in combination with microRNAs (miRs), bind to target mRNAs to initiate degradation and/or translation repression, but the relationships between these two effects is unclear. Although the AGO isoforms of Drosophila and plants perform different functions, mammali...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Ghosh, Utpalendu, Adhya, Samit
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2016
Fag:
RNA
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807293/
https://ncbi.nlm.nih.gov/pubmed/26846850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.696377
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