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Translation of the FMR1 mRNA is not influenced by AGG interruptions
The fragile X mental retardation 1 (FMR1) gene contains a CGG-repeat element within its 5′ untranslated region (5′UTR) which, for alleles with more than ∼40 repeats, increasingly affects both transcription (up-regulation) and translation (inhibition) of the repeat-containing RNA with increasing CGG-...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2777427/ https://ncbi.nlm.nih.gov/pubmed/19752155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp713 |
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