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Non-equivalent Roles of AGO1 and AGO2 in mRNA Turnover and Translation of Cyclin D1 mRNA

Mammalian Argonaute proteins (AGO1–4), in combination with microRNAs (miRs), bind to target mRNAs to initiate degradation and/or translation repression, but the relationships between these two effects is unclear. Although the AGO isoforms of Drosophila and plants perform different functions, mammali...

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Vydáno v:J Biol Chem
Hlavní autoři: Ghosh, Utpalendu, Adhya, Samit
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
Témata:
RNA
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807293/
https://ncbi.nlm.nih.gov/pubmed/26846850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.696377
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