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Non-equivalent Roles of AGO1 and AGO2 in mRNA Turnover and Translation of Cyclin D1 mRNA

Mammalian Argonaute proteins (AGO1–4), in combination with microRNAs (miRs), bind to target mRNAs to initiate degradation and/or translation repression, but the relationships between these two effects is unclear. Although the AGO isoforms of Drosophila and plants perform different functions, mammali...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Ghosh, Utpalendu, Adhya, Samit
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807293/
https://ncbi.nlm.nih.gov/pubmed/26846850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.696377
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