Evaluation of Interferon Resistance in Newly Established Genotype 1b Hepatitis C Virus Cell Culture System

Background and Aims: The hepatitis C virus (HCV) genotype 1b is known to exhibit treatment resistance with respect to interferon (IFN) therapy. Substitution of amino acids 70 and 91 in the core region of the 1b genotype is a significant predictor of liver carcinogenesis and poor response to pegylate...

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Detalhes bibliográficos
Publicado no:J Clin Transl Hepatol
Main Authors: Taniguchi, Miki, Tasaka-Fujita, Megumi, Nakagawa, Mina, Watanabe, Takako, Kawai-Kitahata, Fukiko, Otani, Satoshi, Goto, Fumio, Nagata, Hiroko, Kaneko, Shun, Nitta, Sayuri, Murakawa, Miyako, Nishimura-Sakurai, Yuki, Azuma, Seishin, Itsui, Yasuhiro, Mori, Kenichi, Yagi, Shintaro, Kakinuma, Sei, Asahina, Yasuhiro, Watanabe, Mamoru
Formato: Artigo
Idioma:Inglês
Publicado em: XIA & HE Publishing Inc. 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807137/
https://ncbi.nlm.nih.gov/pubmed/27047766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14218/JCTH.2015.00047
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