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Human induced pluripotent stem cell-derived hepatic cell lines as a new model for host interaction with hepatitis B virus

Hepatitis B virus (HBV) is not eradicated by current antiviral therapies due to persistence of HBV covalently closed circular DNA (cccDNA) in host cells, and thus development of novel culture models for productive HBV infection is urgently needed, which will allow the study of HBV cccDNA eradication...

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Publicado no:Sci Rep
Main Authors: Kaneko, Shun, Kakinuma, Sei, Asahina, Yasuhiro, Kamiya, Akihide, Miyoshi, Masato, Tsunoda, Tomoyuki, Nitta, Sayuri, Asano, Yu, Nagata, Hiroko, Otani, Satoshi, Kawai-Kitahata, Fukiko, Murakawa, Miyako, Itsui, Yasuhiro, Nakagawa, Mina, Azuma, Seishin, Nakauchi, Hiromitsu, Nishitsuji, Hironori, Ujino, Saneyuki, Shimotohno, Kunitada, Iwamoto, Masashi, Watashi, Koichi, Wakita, Takaji, Watanabe, Mamoru
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937433/
https://ncbi.nlm.nih.gov/pubmed/27386799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29358
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