Mice Lacking Endoglin in Macrophages Show an Impaired Immune Response

Endoglin is an auxiliary receptor for members of the TGF-β superfamily and plays an important role in the homeostasis of the vessel wall. Mutations in endoglin gene (ENG) or in the closely related TGF-β receptor type I ACVRL1/ALK1 are responsible for a rare dominant vascular dysplasia, the Hereditar...

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Vydáno v:PLoS Genet
Hlavní autoři: Ojeda-Fernández, Luisa, Recio-Poveda, Lucía, Aristorena, Mikel, Lastres, Pedro, Blanco, Francisco J., Sanz-Rodríguez, Francisco, Gallardo-Vara, Eunate, de las Casas-Engel, Mateo, Corbí, Ángel, Arthur, Helen M., Bernabeu, Carmelo, Botella, Luisa M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806930/
https://ncbi.nlm.nih.gov/pubmed/27010826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005935
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