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Ligand-Dependent Conformational Dynamics of Dihydrofolate Reductase
Enzymes are known to change among several conformational states during turnover. The role of such dynamic structural changes in catalysis is not fully understood. The influence of dynamics in catalysis can be inferred, but not proven, by comparison of equilibrium structures of protein variants and p...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4806677/ https://ncbi.nlm.nih.gov/pubmed/26901612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b01364 |
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