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Tumour imaging by the detection of fibrin clots in tumour stroma using an anti-fibrin Fab fragment

The diagnosis of early and aggressive types of cancer is important for providing effective cancer therapy. Cancer-induced fibrin clots exist only within lesions. Previously, we developed a monoclonal antibody (clone 102-10) that recognizes insoluble fibrin but not fibrinogen or soluble fibrin and co...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Obonai, Toshifumi, Fuchigami, Hirobumi, Furuya, Fumiaki, Kozuka, Naoyuki, Yasunaga, Masahiro, Matsumura, Yasuhiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806360/
https://ncbi.nlm.nih.gov/pubmed/27009516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23613
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