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Label-free Imaging of Microtubules with Sub-nm Precision Using Interferometric Scattering Microscopy
Current in vitro optical studies of microtubule dynamics tend to rely on fluorescent labeling of tubulin, with tracking accuracy thereby limited by the quantum yield of fluorophores and by photobleaching. Here, we demonstrate label-free tracking of microtubules with nanometer precision at kilohertz...
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| Publicado en: | Biophys J |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Biophysical Society
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4806212/ https://ncbi.nlm.nih.gov/pubmed/26745424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.10.055 |
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